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Organic Chemistry for Chemical Biology and Biomedical Applications
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New Concepts in Chemical Synthesis and Reactivity
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Academic year 2022/2023
- Teaching staff
- Andrea Fin (Titolare del corso)
Francesca Cardano (Titolare del corso) - Teaching period
- Second semester
- Type
- Basic
- Credits/Recognition
- 3
- Course disciplinary sector (SSD)
- CHIM/06 - organic chemistry
- Delivery
- Formal authority
- Language
- English
- Attendance
- Obligatory
- Type of examination
- Quiz
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Sommario del corso
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Course objectives
Bioinspired synthetic molecules, photo-controlled compounds and functionals probes are increasingly gaining importance in life science investigations, opening new possibilities in biomedical applications with significant impact on eminent clinical potentialities.
From the synthesis of aspirin to the synthetic xenobiology, the precise light guided spatiotemporal control of functional activity, and real-time fluorescence image-guided surgery, synthetic organic molecules have played a crucial role in many scientific achievements.
The course will cover an historical overview and a critical analysis of last achievements in the field of the bioinspired synthetic molecules, photoregulation of biological systems and pharmaceutical compounds along with the description of functional probes for application in biological relevant processes, pre-clinical and clinical bioimaging, as well as, in the synthetic development of photopharmacological and diagnostics tools.- Oggetto:
Program
- Historical overview of relevant synthetic organic molecules of biological or therapeutic relevance.
- Organic chemistry tackling COVID-19.
- Synthetic efforts to expand the central dogma of molecular biology.
- Synthetic molecules and materials at the farefront of gene delivery.
- To see or not to see: organic synthetic probes to shed light on life processes and domains.
- Life and light the success of photopharmacology: concepts and synthetic challenges.
- Photopharmacology on stage: on overview on targeted applications
Suggested readings and bibliography
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Note
Provisional schedule
05/06/2023 - 9-11 Aula Disegno, Department of Chemistry, Via Giuria 7
07/06/2023 - 9-11 Aula Disegno, Department of Chemistry, Via Giuria 7
09/06/2023 - 9-11 Aula Disegno, Department of Chemistry, Via Giuria 7
12/06/2023 - 9-11 Aula Disegno, Department of Chemistry, Via Giuria 7
14/06/2023 - 9-11 Aula Disegno, Department of Chemistry, Via Giuria 7
16/06/2023 - 9-11 Aula Disegno, Department of Chemistry, Via Giuria 7
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